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Tissue‐Specific Roles for the Slit–Robo Pathway During Heart, Caval Vein, and Diaphragm Development
BACKGROUND: Binding of Slit ligands to their Robo receptors regulates signaling pathways that are important for heart development. Genetic variants in ROBO1and ROBO4 have been linked to congenital heart defects in humans. These defects are recapitulated in mouse models with ubiquitous deletions of t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075489/ https://www.ncbi.nlm.nih.gov/pubmed/35343246 http://dx.doi.org/10.1161/JAHA.121.023348 |