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Tubastatin A Improves Post‐Resuscitation Myocardial Dysfunction by Inhibiting NLRP3‐Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling

BACKGROUND: Myocardial dysfunction is the leading cause of early death following successful cardiopulmonary resuscitation (CPR) in people with cardiac arrest (CA), which is potentially driven by cell pyroptosis mediated by NOD‐like receptor pyrin domain 3 (NLRP3) inflammasome. Recently, histone deac...

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Detalles Bibliográficos
Autores principales: Xu, Jiefeng, Zhao, Xue, Jiang, Xiangkang, He, Lu, Wu, Xinjie, Wang, Jiangang, Chen, Qijiang, Li, Yulin, Zhang, Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075499/
https://www.ncbi.nlm.nih.gov/pubmed/35322683
http://dx.doi.org/10.1161/JAHA.121.024205