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Tubastatin A Improves Post‐Resuscitation Myocardial Dysfunction by Inhibiting NLRP3‐Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling
BACKGROUND: Myocardial dysfunction is the leading cause of early death following successful cardiopulmonary resuscitation (CPR) in people with cardiac arrest (CA), which is potentially driven by cell pyroptosis mediated by NOD‐like receptor pyrin domain 3 (NLRP3) inflammasome. Recently, histone deac...
Autores principales: | Xu, Jiefeng, Zhao, Xue, Jiang, Xiangkang, He, Lu, Wu, Xinjie, Wang, Jiangang, Chen, Qijiang, Li, Yulin, Zhang, Mao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075499/ https://www.ncbi.nlm.nih.gov/pubmed/35322683 http://dx.doi.org/10.1161/JAHA.121.024205 |
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