The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways

A comprehensive constellation of somatic nonsilent mutations and copy-number (CN) variations in ocular adnexa marginal zone lymphoma (OAMZL) is unknown. By utilizing whole-exome sequencing in 69 tumors, we define the genetic landscape of OAMZL. Mutations and CN changes in CABIN1 (30%), RHOA (26%), T...

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Detalles Bibliográficos
Autores principales: Magistri, Marco, Happ, Lanie E., Ramdial, Jeremy, Lu, XiaoQing, Stathias, Vasileios, Kunkalla, Kranthi, Agarwal, Nitin, Jiang, Xiaoyu, Schürer, Stephan C., Dubovy, Sander R., Chapman, Jennifer R., Vega, Francisco, Dave, Sandeep, Lossos, Izidore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075502/
https://www.ncbi.nlm.nih.gov/pubmed/35528192
http://dx.doi.org/10.1158/2767-9764.CRC-21-0022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075502/
https://www.ncbi.nlm.nih.gov/pubmed/35528192
http://dx.doi.org/10.1158/2767-9764.CRC-21-0022

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