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The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways
A comprehensive constellation of somatic nonsilent mutations and copy-number (CN) variations in ocular adnexa marginal zone lymphoma (OAMZL) is unknown. By utilizing whole-exome sequencing in 69 tumors, we define the genetic landscape of OAMZL. Mutations and CN changes in CABIN1 (30%), RHOA (26%), T...
Autores principales: | Magistri, Marco, Happ, Lanie E., Ramdial, Jeremy, Lu, XiaoQing, Stathias, Vasileios, Kunkalla, Kranthi, Agarwal, Nitin, Jiang, Xiaoyu, Schürer, Stephan C., Dubovy, Sander R., Chapman, Jennifer R., Vega, Francisco, Dave, Sandeep, Lossos, Izidore S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075502/ https://www.ncbi.nlm.nih.gov/pubmed/35528192 http://dx.doi.org/10.1158/2767-9764.CRC-21-0022 |
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