Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells

Cysteine proteases play a key role in tumorigenesis causing protein degradation and promoting invasive tumour growth. Cathepsin L is overexpressed in cancer cells and could provide a specific target for delivery of anticancer agents. We encapsulated novel dipeptidyl nitrile based cysteine protease i...

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Detalles Bibliográficos
Autores principales: Quilles Junior, José C., Carlos, Fernanda dos Reis Rocho, Montanari, A., Leitão, Andrei, Mignone, Viviane W., Arruda, Maria Augusta, Turyanska, Lyudmila, Bradshaw, Tracey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075514/
https://www.ncbi.nlm.nih.gov/pubmed/35539052
http://dx.doi.org/10.1039/c9ra07161j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075514/
https://www.ncbi.nlm.nih.gov/pubmed/35539052
http://dx.doi.org/10.1039/c9ra07161j

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