Use of paclitaxel carried in solid lipid nanoparticles to prevent peritoneal fibrosis in rats

BACKGROUND: Progressive fibrous thickening of peritoneal membrane (PM) is a major complication of long-term peritoneal dialysis. TGF-β/SMAD pathway activation, inflammation and neoangiogenesis have an important role in PM changes induced by peritoneal dialysis. Here, we investigated the effects of p...

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Detalles Bibliográficos
Autores principales: Silva, Filipe M. O., Carvalho, Priscila O., Costalonga, Elerson C., Pepineli, Rafael, Maranhão, Raul C., Noronha, Irene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075628/
https://www.ncbi.nlm.nih.gov/pubmed/35522621
http://dx.doi.org/10.1371/journal.pone.0268197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075628/
https://www.ncbi.nlm.nih.gov/pubmed/35522621
http://dx.doi.org/10.1371/journal.pone.0268197

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