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Use of paclitaxel carried in solid lipid nanoparticles to prevent peritoneal fibrosis in rats

BACKGROUND: Progressive fibrous thickening of peritoneal membrane (PM) is a major complication of long-term peritoneal dialysis. TGF-β/SMAD pathway activation, inflammation and neoangiogenesis have an important role in PM changes induced by peritoneal dialysis. Here, we investigated the effects of p...

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Detalles Bibliográficos
Autores principales:	Silva, Filipe M. O., Carvalho, Priscila O., Costalonga, Elerson C., Pepineli, Rafael, Maranhão, Raul C., Noronha, Irene L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075628/ https://www.ncbi.nlm.nih.gov/pubmed/35522621 http://dx.doi.org/10.1371/journal.pone.0268197

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