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Dnmt1a is essential for gene body methylation and the regulation of the zygotic genome in a wasp

Gene body methylation (GBM) is an ancestral mode of DNA methylation whose role in development has been obscured by the more prominent roles of promoter and CpG island methylation. The wasp Nasonia vitripennis has little promoter and CpG island methylation, yet retains strong GBM, making it an excell...

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Detalles Bibliográficos
Autores principales: Arsala, Deanna, Wu, Xin, Yi, Soojin V., Lynch, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075658/
https://www.ncbi.nlm.nih.gov/pubmed/35522715
http://dx.doi.org/10.1371/journal.pgen.1010181