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AMP activated kinase negatively regulates hepatic Fetuin-A via p38 MAPK-C/EBPβ/E3 Ubiquitin Ligase Signaling pathway

Fetuin-A (Fet-A) is a liver-secreted phosphorylated protein, known to impair insulin signaling, which has been shown to be associated with obesity, insulin resistance, and incident diabetes. Fet-A interacts with the insulin-stimulated insulin receptor (IR) and inhibits IR tyrosine kinase activity an...

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Detalles Bibliográficos
Autores principales: Kothari, Vishal, Babu, Jeganathan Ramesh, Mathews, Suresh T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075660/
https://www.ncbi.nlm.nih.gov/pubmed/35522655
http://dx.doi.org/10.1371/journal.pone.0266472