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Circulating inflammatory monocytes oppose microglia and contribute to cone cell death in retinitis pigmentosa

Retinitis pigmentosa (RP) is an intractable inherited disease that primarily affects the rods through gene mutations followed by secondary cone degeneration. This cone-related dysfunction can lead to impairment of daily life activities, and ultimately blindness in patients with RP. Paradoxically, mi...

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Detalles Bibliográficos
Autores principales: Funatsu, Jun, Murakami, Yusuke, Shimokawa, Shotaro, Nakatake, Shunji, Fujiwara, Kohta, Okita, Ayako, Fukushima, Masatoshi, Shibata, Kensuke, Yoshida, Noriko, Koyanagi, Yoshito, Akiyama, Masato, Notomi, Shoji, Nakao, Shintaro, Hisatomi, Toshio, Takeda, Atsunobu, Paschalis, Eleftherios I, Vavvas, Demetrios G, Ikeda, Yasuhiro, Sonoda, Koh-Hei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075747/
https://www.ncbi.nlm.nih.gov/pubmed/35529318
http://dx.doi.org/10.1093/pnasnexus/pgac003