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A Maitake (Grifola frondosa) polysaccharide ameliorates Alzheimer's disease-like pathology and cognitive impairments by enhancing microglial amyloid-β clearance

Alzheimer's disease (AD) is characterized by the deposition of amyloid-β (Aβ) plaques, neuronal loss and neurofibrillary tangles. In addition, neuroinflammatory processes are thought to contribute to AD pathophysiology. Maitake (Grifola frondosa), an edible/medicinal mushroom, exhibits high nut...

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Detalles Bibliográficos
Autores principales: Bai, Yao, Chen, Lingling, Chen, Yao, Chen, Xinmeng, Dong, Yilong, Zheng, Shangyong, Zhang, Lei, Li, Weiyuan, Du, Jing, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075749/
https://www.ncbi.nlm.nih.gov/pubmed/35542273
http://dx.doi.org/10.1039/c9ra08245j