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Resonant waveguide grating based assays for colloidal aggregate detection and promiscuity characterization in natural products

Small molecules, including natural compounds, in aqueous buffer that self-associate into colloidal aggregates is the main cause of false results in the early stage of drug discovery. Here we reported resonant waveguide grating (RWG) based assays to identify natural compound aggregation and character...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Wang, Jixia, Liu, Yanfang, Zhang, Xiuli, Liang, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075791/
https://www.ncbi.nlm.nih.gov/pubmed/35541809
http://dx.doi.org/10.1039/c9ra06466d