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Resonant waveguide grating based assays for colloidal aggregate detection and promiscuity characterization in natural products
Small molecules, including natural compounds, in aqueous buffer that self-associate into colloidal aggregates is the main cause of false results in the early stage of drug discovery. Here we reported resonant waveguide grating (RWG) based assays to identify natural compound aggregation and character...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075791/ https://www.ncbi.nlm.nih.gov/pubmed/35541809 http://dx.doi.org/10.1039/c9ra06466d |