Rapid, site-specific labeling of “off-the-shelf” and native serum autoantibodies with T cell–redirecting domains

Extensive antibody engineering and cloning is typically required to generate new bispecific antibodies. Made-to-order genes, advanced expression systems, and high-efficiency cloning can simplify and accelerate this process, but it still can take months before a functional product is realized. We dev...

Descripción completa

Detalles Bibliográficos
Autores principales: Zappala, Fabiana, Higbee-Dempsey, Elizabeth, Jang, Bian, Miller, Joann, Yan, Lesan, Minutolo, Nicholas G., Rosado González, Gabriela T., Tsourkas, Andrew, Ozdemir, Burcin Altun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075798/
https://www.ncbi.nlm.nih.gov/pubmed/35522741
http://dx.doi.org/10.1126/sciadv.abn4613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075798/
https://www.ncbi.nlm.nih.gov/pubmed/35522741
http://dx.doi.org/10.1126/sciadv.abn4613

Ejemplares similares