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Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits

Parvalbumin-positive (PV(+)) interneurons play a critical role in maintaining circuit rhythm in the brain, and their reduction is implicated in autism spectrum disorders. Animal studies demonstrate that maternal immune activation (MIA) leads to reduced PV(+) interneurons in the somatosensory cortex...

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Detalles Bibliográficos
Autores principales: Yu, Diankun, Li, Tao, Delpech, Jean-Christophe, Zhu, Beika, Kishore, Priya, Koshi, Tatsuhiro, Luo, Rong, Pratt, Karishma J.B., Popova, Galina, Nowakowski, Tomasz J., Villeda, Saul A., Piao, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075805/
https://www.ncbi.nlm.nih.gov/pubmed/35544642
http://dx.doi.org/10.1126/sciadv.abm2545