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Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits
Parvalbumin-positive (PV(+)) interneurons play a critical role in maintaining circuit rhythm in the brain, and their reduction is implicated in autism spectrum disorders. Animal studies demonstrate that maternal immune activation (MIA) leads to reduced PV(+) interneurons in the somatosensory cortex...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075805/ https://www.ncbi.nlm.nih.gov/pubmed/35544642 http://dx.doi.org/10.1126/sciadv.abm2545 |