Cargando…

H3K4me3 recognition by the COMPASS complex facilitates the restoration of this histone mark following DNA replication

During DNA replication, parental H3-H4 marked by H3K4me3 are transferred almost equally onto leading and lagging strands of DNA replication forks. Mutations in replicative helicase subunit, Mcm2 (Mcm2-3A), and leading strand DNA polymerase subunit, Dpb3 (dpb3∆), result in asymmetric distributions of...

Descripción completa

Detalles Bibliográficos
Autores principales: Serra-Cardona, Albert, Duan, Shoufu, Yu, Chuanhe, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075808/
https://www.ncbi.nlm.nih.gov/pubmed/35544640
http://dx.doi.org/10.1126/sciadv.abm6246