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Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis via suppressing NFATc1 activation

Excessive osteoclastogenesis and enhanced bone resorption are pathological hallmarks for bone diseases including osteolytic diseases, osteoporosis, and arthritis. Treatments targeting highly activated osteoclasts are regarded as promising therapies for osteoclast-related bone disorders. Cytochalasin...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Chen, Kai, He, Jianbo, Kenny, Jacob, Yuan, Yu, Chen, Junhao, Liu, Qian, Tan, Renxiang, Zhao, Jinmin, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075846/
https://www.ncbi.nlm.nih.gov/pubmed/35540197
http://dx.doi.org/10.1039/c9ra07240c