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A Ternary Synergistic eNOS Gene Delivery System Based on Calcium Ion and L-Arginine for Accelerating Angiogenesis by Maximizing NO Production

PURPOSE: This study aimed to construct a delivery system based on L-arginine-modified calcium phosphate (CaP) to load eNOS plasmids (peNOS), which could amply nitric oxide (NO) to repair endothelial damage, promote angiogenic activities and alleviate inflammation. METHODS: pDNA-loaded CaP nanocomple...

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Detalles Bibliográficos
Autores principales: Zhang, Guiming, Han, Shangcong, Wang, Lisheng, Yao, Yu, Chen, Kai, Chen, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075900/
https://www.ncbi.nlm.nih.gov/pubmed/35530975
http://dx.doi.org/10.2147/IJN.S363168