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The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma

BACKGROUND: Solute carrier family 7 member 11 (SLC7A11) is overexpressed in multiple human tumours and functions as a transporter importing cystine for glutathione biosynthesis. It promotes tumour development in part by suppressing ferroptosis, a newly identified form of cell death that plays a pivo...

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Detalles Bibliográficos
Autores principales: Liu, Li, He, Jiangtu, Sun, Guifeng, Huang, Nan, Bian, Zhixuan, Xu, Chang, Zhang, Yue, Cui, Zhongqi, Xu, Wenqiang, Sun, Fenyong, Zhuang, Chengle, Man, Qiuhong, Gu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076012/
https://www.ncbi.nlm.nih.gov/pubmed/35522946
http://dx.doi.org/10.1002/ctm2.778