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Exosome‐transmitted miR‐769‐5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53

BACKGROUND: Cisplatin resistance is the main cause of poor clinical prognosis in patients with gastric cancer (GC). Yet, the exact mechanism underlying cisplatin resistance remains unclear. Recent studies have suggested that exocrine miRNAs found in the tumor microenvironment participate in tumor me...

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Detalles Bibliográficos
Autores principales: Jing, Xinming, Xie, Mengyan, Ding, Kun, Xu, Tingting, Fang, Yuan, Ma, Pei, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076018/
https://www.ncbi.nlm.nih.gov/pubmed/35522909
http://dx.doi.org/10.1002/ctm2.780