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Biophysical Fitness Landscape of the SARS-CoV-2 Delta Variant Receptor Binding Domain

Among the five known SARS-CoV-2 variants of concern, Delta is the most virulent leading to severe symptoms and increased mortality among infected people. Our study seeks to examine how the biophysical parameters of the Delta variant correlate to the clinical observations. Receptor binding domain (RB...

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Detalles Bibliográficos
Autores principales: Patrick, Casey, Upadhyay, Vaibhav, Lucas, Alexandra, Mallela, Krishna M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076029/
https://www.ncbi.nlm.nih.gov/pubmed/35533762
http://dx.doi.org/10.1016/j.jmb.2022.167622