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Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins

Betulinic acid and ursolic acid are ubiquitous, naturally-occurring triterpenoids exhibiting various pharmacological activities including cytotoxic and anti-inflammatory activities. However, these triterpenoids display unfavorable pharmacokinetic properties as well as low aqueous solubility. It has...

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Detalles Bibliográficos
Autores principales: Sylla, Balla, Lavoie, Serge, Legault, Jean, Gauthier, Charles, Pichette, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076072/
https://www.ncbi.nlm.nih.gov/pubmed/35541393
http://dx.doi.org/10.1039/c9ra09389c