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The inhibiting role of hydroxypropylmethylcellulose acetate succinate on piperine crystallization to enhance its dissolution from its amorphous solid dispersion and permeability

The purpose of this study was to demonstrate that inhibiting crystallization by HPMCAS played a key role in enhancing dissolution and absorption of piperine (Pip) from its amorphous solid dispersion (ASD). Nucleation induction time and supersaturation tests were used to evaluate the ability of the p...

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Detalles Bibliográficos
Autores principales: Deng, Yueyi, Liang, Qi, Wang, Yiru, Zhang, Xiaolan, Yan, Chengyun, He, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076092/
https://www.ncbi.nlm.nih.gov/pubmed/35540632
http://dx.doi.org/10.1039/c9ra08283b