Cargando…

In silico study on identification of novel MALT1 allosteric inhibitors

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), which plays a crucial role in the nuclear factor-kappa B (NF-κB) activation signaling pathway as a paracaspase, is a new target for immunomodulatory and antitumor drugs. Here, novel inhibitors that target MALT1 allosteric si...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jinrui, Ren, Li, Wang, Ye, Fang, Xuexun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076111/
https://www.ncbi.nlm.nih.gov/pubmed/35540679
http://dx.doi.org/10.1039/c9ra07036b