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RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53

BACKGROUND: Although N6-methyladenosine (m(6)A) RNA methylation is the most abundant reversible methylation of mRNA, which plays a critical role in regulating cancer processing, few studies have examined the role of m(6)A in nonsmall-cell lung cancer-derived cancer stem-like cells (CSCs). METHODS: C...

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Detalles Bibliográficos
Autores principales: Liu, Xiangli, Wang, Ziyi, Yang, Qiwei, Hu, Xiaohai, Fu, Qiang, Zhang, Xinyu, Li, Wenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076132/
https://www.ncbi.nlm.nih.gov/pubmed/35530319
http://dx.doi.org/10.3389/fonc.2022.858694