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Discovery of a novel small molecular peptide that disrupts helix 34 of bacterial ribosomal RNA

Despite the advances in modern medicine, antibiotic resistance is a persistent and growing threat to the world. Thus, the discovery and development of novel antibiotics have become crucial to combat multi-drug resistant pathogens. The goal of our research is to discover a small molecular peptide tha...

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Detalles Bibliográficos
Autores principales: GC, Keshav, To, Davidnhan, Jayalath, Kumudie, Abeysirigunawardena, Sanjaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076165/
https://www.ncbi.nlm.nih.gov/pubmed/35542650
http://dx.doi.org/10.1039/c9ra07812f