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Pd-catalyzed intramolecular addition of active methylene compounds to alkynes with subsequent cross-coupling with (hetero)aryl halides

We report an efficient protocol for tandem Pd-catalyzed intramolecular addition of active methylene compounds to alkynes, followed by subsequent cross-coupling with (hetero)aryl bromides and chlorides. The reaction proceeds under mild conditions, providing excellent functional group tolerance, inclu...

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Detalles Bibliográficos
Autores principales: Błocka, Aleksandra, Woźnicki, Paweł, Stankevič, Marek, Chaładaj, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076196/
https://www.ncbi.nlm.nih.gov/pubmed/35541417
http://dx.doi.org/10.1039/c9ra08002c