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Characterization of an SSB–dT25 complex: structural insights into the S-shaped ssDNA binding conformation

Single-stranded DNA (ssDNA)-binding proteins (SSBs) play an important role in all DNA-dependent cellular processes, such as DNA replication, recombination, repair, and replication restart. The N-terminal domain of SSBs forms an oligonucleotide/oligosaccharide-binding (OB) fold for ssDNA binding. The...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Hua, Chen, I-Chen, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076272/
https://www.ncbi.nlm.nih.gov/pubmed/35542687
http://dx.doi.org/10.1039/c9ra09406g