LCZ696 Ameliorates Isoproterenol-Induced Acute Heart Failure in Rats by Activating the Nrf2 Signaling Pathway

OBJECTIVE: LCZ696 (sacubitril/valsartan) is an angiotensin II (Ang II) type 1 receptor-neprilysin inhibitor, with effects of immunosuppression, anti-inflammation, antiapoptosis, and antioxidation. The present study was aimed at determining whether LCZ696 has a protective effect against isoproterenol...

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Detalles Bibliográficos
Autores principales: Hou, Min, Lu, Linxin, Wu, Xiaobo, Liu, Hongxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076311/
https://www.ncbi.nlm.nih.gov/pubmed/35528528
http://dx.doi.org/10.1155/2022/6077429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076311/
https://www.ncbi.nlm.nih.gov/pubmed/35528528
http://dx.doi.org/10.1155/2022/6077429

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