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LCZ696 Ameliorates Isoproterenol-Induced Acute Heart Failure in Rats by Activating the Nrf2 Signaling Pathway

OBJECTIVE: LCZ696 (sacubitril/valsartan) is an angiotensin II (Ang II) type 1 receptor-neprilysin inhibitor, with effects of immunosuppression, anti-inflammation, antiapoptosis, and antioxidation. The present study was aimed at determining whether LCZ696 has a protective effect against isoproterenol...

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Detalles Bibliográficos
Autores principales:	Hou, Min, Lu, Linxin, Wu, Xiaobo, Liu, Hongxuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076311/ https://www.ncbi.nlm.nih.gov/pubmed/35528528 http://dx.doi.org/10.1155/2022/6077429

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