Scn1b expression in the adult mouse heart modulates Na(+) influx in myocytes and reveals a mechanistic link between Na(+) entry and diastolic function

Voltage-gated sodium channels (VGSCs) are macromolecular assemblies composed of a number of proteins regulating channel conductance and properties. VGSCs generate Na(+) current (I(Na)) in myocytes and play fundamental roles in excitability and impulse conduction in the heart. Moreover, VGSCs conditi...

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Detalles Bibliográficos
Autores principales: Cervantes, Daniel O., Pizzo, Emanuele, Ketkar, Harshada, Parambath, Sreema P., Tang, Samantha, Cianflone, Eleonora, Cannata, Antonio, Vinukonda, Govindaiah, Jain, Sudhir, Jacobson, Jason T., Rota, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076421/
https://www.ncbi.nlm.nih.gov/pubmed/35394857
http://dx.doi.org/10.1152/ajpheart.00465.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076421/
https://www.ncbi.nlm.nih.gov/pubmed/35394857
http://dx.doi.org/10.1152/ajpheart.00465.2021

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