PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38(MAPK) signalling

Glioblastoma (GBM) is the most common and fatal primary brain tumour in adults. Considering that resistance to current therapies leads to limited response in patients, new therapeutic options are urgently needed. In recent years, differentiation therapy has been proposed as an alternative for GBM tr...

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Detalles Bibliográficos
Autores principales: Lane, Rosemary, Cilibrasi, Chiara, Chen, Jianing, Shah, Kalpit, Messuti, Eleonora, Mazarakis, Nektarios K., Stebbing, Justin, Critchley, Giles, Song, Erwei, Simon, Thomas, Giamas, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076540/
https://www.ncbi.nlm.nih.gov/pubmed/35393545
http://dx.doi.org/10.1038/s41388-022-02294-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076540/
https://www.ncbi.nlm.nih.gov/pubmed/35393545
http://dx.doi.org/10.1038/s41388-022-02294-x

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