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PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38(MAPK) signalling
Glioblastoma (GBM) is the most common and fatal primary brain tumour in adults. Considering that resistance to current therapies leads to limited response in patients, new therapeutic options are urgently needed. In recent years, differentiation therapy has been proposed as an alternative for GBM tr...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076540/ https://www.ncbi.nlm.nih.gov/pubmed/35393545 http://dx.doi.org/10.1038/s41388-022-02294-x |