Novel stereoselective syntheses of N-octyl-β-valienamine (NOV) and N-octyl-4-epi-β-valienamine (NOEV) from (−)-shikimic acid

N-Octyl-β-valienamine (NOV) 1 and N-octyl-4-epi-β-valienamine (NOEV) 2 are potent chemical chaperone drug candidates for the therapy of lysosomal storage disorders. Novel stereoselective syntheses of NOV 1 and NOEV 2 starting from naturally abundant (−)-shikimic acid are described in this article. T...

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Detalles Bibliográficos
Autores principales: Li, Feng-Lei, Yu, Jiang-Ping, Ding, Wei, Sun, Mian-Mian, He, Yun-Gang, Zhu, Xing-Liang, Liu, Shi-Ling, Shi, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076550/
https://www.ncbi.nlm.nih.gov/pubmed/35542836
http://dx.doi.org/10.1039/c9ra09235h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076550/
https://www.ncbi.nlm.nih.gov/pubmed/35542836
http://dx.doi.org/10.1039/c9ra09235h

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