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Direct intramolecular double cross-dehydrogentive-coupling (CDC) cyclization of N-(2-pyridyl)amidines under metal-free conditions

A facile transition-metal-free protocol to form 2-iminoimidazo[1, 2-a]-pyridines bearing a –CHBr(2) group and an aza-quaternary carbon center at the 3 position from N-(2-pyridyl)amidines substrates, in which the new heterocyclic skeletons constructed from amidines via radical reactions or nucleophil...

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Detalles Bibliográficos
Autores principales: Yi, Fengping, Fu, Chao, Sun, Qihui, Wei, Huazhen, Yu, Genfa, Yi, Weiyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076575/
https://www.ncbi.nlm.nih.gov/pubmed/35542831
http://dx.doi.org/10.1039/c9ra09265j