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Catalytic asymmetric Tsuji–Trost α−benzylation reaction of N-unprotected amino acids and benzyl alcohol derivatives

Catalytic asymmetric Tsuji–Trost benzylation is a promising strategy for the preparation of chiral benzylic compounds. However, only a few such transformations with both good yields and enantioselectivities have been achieved since this reaction was first reported in 1992, and its use in current org...

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Detalles Bibliográficos
Autores principales: Liu, Jian-Hua, Wen, Wei, Liao, Jian, Shen, Qi-Wen, Lin, Yao, Wu, Zhu-Lian, Cai, Tian, Guo, Qi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076619/
https://www.ncbi.nlm.nih.gov/pubmed/35523802
http://dx.doi.org/10.1038/s41467-022-30277-9