ROCK 1 and 2 affect the spatial architecture of 3D spheroids derived from human corneal stromal fibroblasts in different manners

The objective of the current study was to examine the roles of ROCK1 and 2 on the spatial architecture of human corneal stroma. We examined the effects of a pan-ROCK inhibitor (pan-ROCK-i), ripasudil, and a ROCK2 inhibitor (ROCK2-i), KD025 on the expression of genes that encode for ECM proteins incl...

Descripción completa

Detalles Bibliográficos
Autores principales: Ida, Yosuke, Umetsu, Araya, Furuhashi, Masato, Watanabe, Megumi, Tsugeno, Yuri, Suzuki, Soma, Hikage, Fumihito, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076620/
https://www.ncbi.nlm.nih.gov/pubmed/35523828
http://dx.doi.org/10.1038/s41598-022-11407-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076620/
https://www.ncbi.nlm.nih.gov/pubmed/35523828
http://dx.doi.org/10.1038/s41598-022-11407-1

Ejemplares similares