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ROCK 1 and 2 affect the spatial architecture of 3D spheroids derived from human corneal stromal fibroblasts in different manners

The objective of the current study was to examine the roles of ROCK1 and 2 on the spatial architecture of human corneal stroma. We examined the effects of a pan-ROCK inhibitor (pan-ROCK-i), ripasudil, and a ROCK2 inhibitor (ROCK2-i), KD025 on the expression of genes that encode for ECM proteins incl...

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Detalles Bibliográficos
Autores principales:	Ida, Yosuke, Umetsu, Araya, Furuhashi, Masato, Watanabe, Megumi, Tsugeno, Yuri, Suzuki, Soma, Hikage, Fumihito, Ohguro, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076620/ https://www.ncbi.nlm.nih.gov/pubmed/35523828 http://dx.doi.org/10.1038/s41598-022-11407-1

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