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Distinctive molecular features of regenerative stem cells in the damaged male germline

Maintenance of male fertility requires spermatogonial stem cells (SSCs) that self-renew and generate differentiating germ cells for production of spermatozoa. Germline cells are sensitive to genotoxic drugs and patients receiving chemotherapy can become infertile. SSCs surviving treatment mediate ge...

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Detalles Bibliográficos
Autores principales: La, Hue M., Liao, Jinyue, Legrand, Julien M. D., Rossello, Fernando J., Chan, Ai-Leen, Vaghjiani, Vijesh, Cain, Jason E., Papa, Antonella, Lee, Tin Lap, Hobbs, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076627/
https://www.ncbi.nlm.nih.gov/pubmed/35523793
http://dx.doi.org/10.1038/s41467-022-30130-z