The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

Immune checkpoint molecules play critical roles in regulating the anti-tumor immune response, and tumor cells often exploit these pathways to inhibit and evade the immune system. The B7-family immune checkpoint B7x is widely expressed in a broad variety of cancer types, and is generally associated w...

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Detalles Bibliográficos
Autores principales: John, Peter, Pulanco, Marc C., Galbo, Phillip M., Wei, Yao, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076640/
https://www.ncbi.nlm.nih.gov/pubmed/35523809
http://dx.doi.org/10.1038/s41467-022-30143-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076640/
https://www.ncbi.nlm.nih.gov/pubmed/35523809
http://dx.doi.org/10.1038/s41467-022-30143-8

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