Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

AIMS/HYPOTHESIS: Although targeted in extrapancreatic tissues by several drugs used to treat type 2 diabetes, the role of AMP-activated protein kinase (AMPK) in the control of insulin secretion is still debatable. Previous studies have used pharmacological activators of limited selectivity and speci...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen-Tu, Marie-Sophie, Harris, Joseph, Martinez-Sanchez, Aida, Chabosseau, Pauline, Hu, Ming, Georgiadou, Eleni, Pollard, Alice, Otero, Pablo, Lopez-Noriega, Livia, Leclerc, Isabelle, Sakamoto, Kei, Schmoll, Dieter, Smith, David M., Carling, David, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076735/
https://www.ncbi.nlm.nih.gov/pubmed/35294578
http://dx.doi.org/10.1007/s00125-022-05673-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076735/
https://www.ncbi.nlm.nih.gov/pubmed/35294578
http://dx.doi.org/10.1007/s00125-022-05673-x

Ejemplares similares