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Total synthesis and antimicrobial evaluation of (+)-hygrophorone B(12) and its analogues

This paper describes the synthesis and evaluation of lead compounds with a new chemical skeleton that is not found in conventional antimicrobial agents. The biologically attractive cyclopentenoid (+)-hygrophorone B(12), isolated from the fruiting bodies of Hygrophorus abieticola, and its analogues w...

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Detalles Bibliográficos
Autores principales: Kamishima, Takaaki, Suzuki, Masato, Narita, Koichi, Koseki, Yoshitaka, Nonaka, Toshiyuki, Nakatsuji, Hirotaka, Hattori, Hideo, Kasai, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076842/
https://www.ncbi.nlm.nih.gov/pubmed/35523990
http://dx.doi.org/10.1038/s41598-022-11608-8