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Isolation of endogenous cytosolic DNA from cultured cells

DNA damage caused by genetic instability or extrinsic treatment can induce DNA leakage from the nucleus or mitochondria into the cytosol and activate innate and adaptive immunity. To enable characterization of these endogenous cytosolic DNAs and the mechanisms that produce them, we developed an appr...

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Detalles Bibliográficos
Autores principales: Mosley, Shayla R., Baker, Kristi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076957/
https://www.ncbi.nlm.nih.gov/pubmed/35535161
http://dx.doi.org/10.1016/j.xpro.2022.101165