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Isolation of endogenous cytosolic DNA from cultured cells
DNA damage caused by genetic instability or extrinsic treatment can induce DNA leakage from the nucleus or mitochondria into the cytosol and activate innate and adaptive immunity. To enable characterization of these endogenous cytosolic DNAs and the mechanisms that produce them, we developed an appr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076957/ https://www.ncbi.nlm.nih.gov/pubmed/35535161 http://dx.doi.org/10.1016/j.xpro.2022.101165 |