Cargando…

Targeted delivery of HES5-siRNA with novel polypeptide-modified nanoparticles for hepatocellular carcinoma therapy

For actively targeted delivery of small interfering RNA (siRNA) to solid tumors, we fabricated functionalized selenium nanoparticles (SeNPs) decorated with the polypeptide RGDfC. Herein, RGDfC was used as tumor-targeted moiety and installed onto the surface of SeNPs to enhance the cellular uptake. R...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Yu, Wang, Changbing, Xu, Tiantian, Li, Yinghua, Guo, Min, Lin, Zhengfang, Zhao, Mingqi, Zhu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077277/
https://www.ncbi.nlm.nih.gov/pubmed/35542585
http://dx.doi.org/10.1039/c7ra12461a