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Combined anticancer effects of simvastatin and arsenic trioxide on prostate cancer cell lines via downregulation of the VEGF and OPN isoforms genes

Arsenic trioxide (ATO) and statins have been demonstrated to have anti‐neoplastic properties; however, the data regarding their combination therapy is limited. Thus, we aimed to study the effects of ATO, Simvastatin and their combination in proliferation, apoptosis and pathological angiogenesis in p...

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Detalles Bibliográficos
Autores principales: Mirzaei, Akram, Rashedi, Sina, Akbari, Mohammad Reza, Khatami, Fatemeh, Aghamir, Seyed Mohammad Kazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077302/
https://www.ncbi.nlm.nih.gov/pubmed/35366048
http://dx.doi.org/10.1111/jcmm.17286