METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy

Epigenetic changes are present in many physiological and pathological processes. The N(6)-methyladenosine (m6A) modification is the most common modification in eukaryotic mRNA. However, the role of m6A modification in diabetic nephropathy (DN) remains elusive. Here, we found that m6A modification wa...

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Detalles Bibliográficos
Autores principales: Jiang, Ling, Liu, Xueqi, Hu, Xueru, Gao, Li, Zeng, Hanxu, Wang, Xian, Huang, Yuebo, Zhu, Wei, Wang, Jianan, Wen, Jiagen, Meng, Xiaoming, Wu, Yonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077313/
https://www.ncbi.nlm.nih.gov/pubmed/34995800
http://dx.doi.org/10.1016/j.ymthe.2022.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077313/
https://www.ncbi.nlm.nih.gov/pubmed/34995800
http://dx.doi.org/10.1016/j.ymthe.2022.01.002

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