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Multipurposing CARs: Same engine, different vehicles

T cells genetically engineered to recognize and eliminate tumor cells through synthetic chimeric antigen receptors (CARs) have demonstrated remarkable clinical efficacy against B cell leukemia over the past decade. This therapy is a form of highly personalized medicine that involves genetically modi...

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Detalles Bibliográficos
Autores principales: Hossian, A.K.M. Nawshad, Hackett, Christopher S., Brentjens, Renier J., Rafiq, Sarwish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077369/
https://www.ncbi.nlm.nih.gov/pubmed/35151842
http://dx.doi.org/10.1016/j.ymthe.2022.02.012