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Durability of transgene expression after rAAV gene therapy

Recombinant adeno-associated virus (rAAV) gene therapy has the potential to transform the lives of patients with certain genetic disorders by increasing or restoring function to affected tissues. Following the initial establishment of transgene expression, it is unknown how long the therapeutic effe...

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Detalles Bibliográficos
Autores principales: Muhuri, Manish, Levy, Daniel I., Schulz, Martin, McCarty, Douglas, Gao, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077371/
https://www.ncbi.nlm.nih.gov/pubmed/35283274
http://dx.doi.org/10.1016/j.ymthe.2022.03.004