Cargando…

Isocitrate dehydrogenase 1 mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to ferroptosis

The present study intends to clarify the hypothesis that isocitrate dehydrogenase 1 (IDH1) mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to ferroptosis through the in vitro and in vivo experiments. Cholangiocarcinoma RBE cell line was transfected with IDH1 R132C mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Li, Huang, Yi, Zheng, Lei, Zhu, Zhifa, Wu, Yue, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077397/
https://www.ncbi.nlm.nih.gov/pubmed/35600114
http://dx.doi.org/10.1515/med-2022-0477